OneWorld Biotech offers a proven scientific and systematic approach to successful custom assay design and manufacture. We use custom-designed reagents (proteins, antibodies, conjugated antibodies, and cell lines) and can source assay components from third party vendors. OneWorld Biotech has the capability to create a variety of validated assay systems.
Our immune reagent support service either produces or sources, as appropriate, antigens, antibodies, and kit components, and then validates and manufactures your assays. Assay formats include ELISA, Dip Stick, Lateral Flow, Bead-based (magnetic, latex and fluorescent) multiplex, and western blot. One of the assays we developed is in clinical use now. Please also see Antibody Support Services.
We develop cell-based assays including primary cell translational assays, cell proliferation, cytotoxicity and custom transgenic cell line development for reporter gene assays, FRET-based studies for protein interaction, receptor binding, and pathway analysis. We recently completed the in vitro evaluation of a cancer drug in clinical trials for effectiveness against other cancer cell lines.
We conduct enzymology studies for reagent development and validation, including analysis of Km, Kcat, Kd, Vmax, IC50, Ki, pH characteristics and solvent tolerance.